SCIENTIFIC ADVISORY BOARD

Ian H. Frazer, MD

Dr. Frazer is director of the Diamantina Institute of Cancer, Immunology and Metabolic Medicine, a research institute of the University of Queensland at the Princess Alexandra Hospital in Brisbane. His current research interests include immunoregulation and immunotherapeutic vaccines for papillomavirus associated cancers, for which he holds research funding from several Australian and United States funding bodies, including the National Health and Medical Research Council, the Queensland Cancer Fund and the Cancer Research Institute of New York. His work is the basis of vaccines to prevent cervical cancer recently brought to market by GlaxoSmithKline (CervarixTM) and Merck (GardasilTM). The HPV vaccine is only the second vaccine to be produced using recombinant DNA technology. Dr. Frazer was chosen the 2006 Queenslander of the Year and the 2006 Australian of the Year. He is president of the Cancer Council Australia and has over many years advised the WHO on papillomavirus vaccines. He has received several prestigious awards for his pioneering work on immunology, virology and vaccine development including the John Curtin Medal, the William Coley Medal, the Florey Medal and the Novartis Prize for Clinical Immunology. Dr. Frazer emigrated to Australia in 1981 from Edinburgh, Scotland, to continue his clinical training and to pursue studies in viral immunology and autoimmunity at the Walter and Eliza Hall Institute of Medical Research with Professor Ian Mackay.


Duane J. Gubler, Sc.D.,

Dr. Gubler is Professor and Director of the Program in Emerging Infectious Diseases at the Duke NUS Graduate Medical School Singapore. He is also Professor, and former Chair, of the Department of Tropical Medicine and Medical Microbiology at the John A. Burns School of Medicine, University of Hawaii-Manoa, in Honolulu. Dr. Gubler is Director of the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases, and Principal Investigator and Founding Director of the National Institutes of Health Pacific Regional Biosafety Laboratory currently under development at the University of Hawaii. He also hold positions as Adjunct Professor of International Health, Johns Hopkins School of Hygiene and Public Health and Adjunct Professor of Microbiology, Colorado State University. Dr. Gubler is the former Director of the Division of Vector-Borne Infectious Diseases of the Centers for Disease Control and Prevention in Fort Collins, Colorado.


M.J. “Jay” Winship, MD

Dr. Winship has wide experience in drug and device development from concept through Pharm/Tox, CMC, Regulatory and FDA clinical trials phase I-IV. Dr. Winship has been a pharmaceutical executive with experience in both small life science firms and large pharmaceutical companies. He has successfully developed and completed both development plans and commercialization strategies. He has conducted or participated in clinical trials for vaccines, antibodies, cancer, allergy, cytokines, and small molecules (caspase inhibitors). In addition, he is experienced in medical affairs, filing INDs and NDAs. Dr. Winship has formulated and implemented a product compound development program from the benchtop into the clinic in start-up companies and participated in the marketing development. He has also integrated the core competencies of drug and development in 3 separate therapeutic areas and participated in overall strategy. One of his strengths is the understanding of the product use in the clinical medicine setting. He has experienced all the areas of medicine and has been a consultant in Internal Medicine and Infectious Diseases. Dr. Winship has an understanding of the other specialties of medical practice and in addition, as a laboratory director, diagnostics are well understood.